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Columbus laboratory receives grants to study membrane proteins

While cell membrane proteins are abundant, constituting about 25 percent of the typical cell genome, scientists understand the molecular architecture of only about 100 of these cell “gatekeepers,” which selectively mediate the flow of information and nutrients across the walls of the cell from external environments.
Linda Columbus aims to know much more. Armed with nearly $1.7 million in new funding from the National Institutes of Health and the National Science Foundation, Columbus, an assistant professor of chemistry at the University of Virginia, is bridging the gaps in knowledge of how these membrane proteins work, and how they might be regulated to allow in certain drug chemicals, or to keep out invading antigens.

Read more at UVA Today


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