Events & Seminars > Upcoming Events & Seminars

From C-C agostic interactions to C-H bond activation

Despite their relative scarcity, agostic complexes where a CC,[1] rather than a CH, bond interacts with a main group or transition metal have been attracting strong attention recently. This stems from their involvement in metallacyclobutanes that are intermediates in alkene metathesis reactions,[2] and also in their ability to model CC s-complexes and CC bond cleavage.[3] […]

Discovery of a New Type of Catalytic Site Involving Nano-Gold Particles

     Just two years ago, Izzie Green, working in my group in Chemistry at UVa, along with Matt Neurock and Wenjie Tang in Chemical Engineering, discovered a new type of catalytic site involving ~ 3nm diameter Au particles supported on TiO2[1,2].  This site has the remarkable property of catalyzing the oxidation of a variety of […]

Chemistry for Global Health: designing new interventions against Anopheles gambiae, the malaria mosquito

Global Health is the health of populations in a global context, that transcends the perspectives and concerns of individual nations. What impact can organic chemistry have on Global Health? In this seminar I will describe our multidisciplinary, collaborative research to develop new human-safe insecticides against Anopheles gambiae, the “most dangerous animal,” responsible for nearly 700,000 deaths annually. […]

Does Evolution Care About Quantum Mechanics? Electrons, Bioenergetics, and Life

Charge-transfer reactions lie at the heart of photosynthesis and respiration, biocatalysis, disease-related oxidative stress, and nanoscience.  Many charge-transfer reactions involve electron tunneling, and are therefore intrinsically quantum mechanical in nature. Evolution is challenged to manipulate the propagation of electrons in these complex and fluctuating systems [1,2].  The aim of my presentation is to summarize the […]

Molecular Dynamics, Spin Relaxatin, and Magnetic Image Contrast

Beyond The Periodic Table: Role of Superatoms

Nearly twenty years ago it was predicted that stable atomic clusters with specific size and composition and mimicking the chemistry of atoms in the periodic table can be designed and synthesized [1]. These clusters known as “superatoms” can then form the building blocks of a new three-dimensional periodic table and the basis for cluster assembled […]

Hydrogel-Actuated Integrated Responsive Systems (HAIRS): Moving Towards Adaptive, Homeostatic Materials

Dynamic structures that respond reversibly to changes in their environment are central to self-regulating thermal and lighting systems, targeted drug delivery, sensors, and self-propelled locomotion. Since an adaptive change requires energy input, an ideal strategy would be to design materials that harvest energy directly from the environment and use it to drive an appropriate response. […]

Current- and Light-Driven Dynamics in Molecular-Scale Electronics

  Professor Seideman’s website Abstract:  Inelastic electron tunneling via molecular-scale junctions can induce a variety of fascinating dynamical processes in the molecular moiety. These include vibration, rotation, inter-mode energy flow and reaction. Potential applications of current-driven dynamics in heterojunctions range from new forms of molecular machines and new modes of  conduction, to new directions in […]

MARIE PAYNE GRAHAM LECTURE – A Scientific Analysis of 21st Century Environmental and Economic Challenges – Professor Sir David King

Sir David’s website Abstract: Unprecedented improvements in human wellbeing over the nineteenth and twentieth centuries have been driven largely by developments flowing from advances in engineering, medicine, agriculture and technology, and by political and economic developments coupled to consumerism.  But a necessary consequence of these successes has been an equally unprecedented growth in the global […]

How do Students Learn to Use Representations in Chemistry – Professor Melanie Cooper

Professor Cooper’s website Abstract: Molecular level structures and processes must, by necessity, be depicted using representations that “stand in” for the atoms and molecules themselves. Students must learn to use these representations with facility, otherwise they are doomed to memorize and regurgitate, rather than synthesize and use their knowledge in new situations. Nowhere is this […]

MARIE PAYNE GRAHAM LECTURE – Controlling Reactivity of Solid Surfaces: A Fundamental Approach – Professor Sir David A. King

Sir David’s website

HECHT LECTURE: Can DNA Function as a Natural Molecular Switch in Cells? – Professor Laurence Hurley

Probing the α-Synuclein-Membrane Interface by Photons and Neutrons – Dr. Jennifer Lee

Expanding Our Knowledge of Nature’s Chemical Diversity – Professor Jon Clardy

Professor Clardy’s webpage

MD Simulations of Telomerase RNA Pseudoknot and Ribosome Assembly – Professor Sam Cho

Professor Cho’s webpage Abstract — It remains a great challenge to understand how protein and RNA biomolecules fold into well-defined structures that correspond to functions in the cell. Biomolecular computer simulations have greatly improved our ability to identify and characterize the folding pathways and intermediates, but the computational demands of evaluating the forces involved restrict […]

Some Current Challenges in the Conversion of the Biomass-Derived Molecules over Supported Metal Catalysts – Professor Robert Davis

Professor Davis’ webpage Abstract: The conversion of biorenewable feedstocks to fuels and chemicals is one approach to partially relieve our growing dependence on fossil fuels.  However, there are many scientific and engineering challenges to overcome.  In this work, the selective catalytic oxidation of the model polyol glycerol to glyceric acid has been investigated over supported […]

Modern Alchemy: Base Metal Catalysis – Professor Paul Chirik

Professor Chirik’s webpage Abstract: Transition metal catalyzed reactions have revolutionized the art of chemical synthesis. Applications range from the selective synthesis of single enantiomer drugs to the bulk production of the plastic coatings on your mobile phone. In most cases, these reactions rely on second and third row metals such as Pt, Pd, Rh, and […]

Radical Involvement in Enzyme Catalysis – Professor Gary Gerfen

Professor Gerfen’s webpage. Abstract:  “Radical Enzymes” utilize amino acid based radical species to catalyze reactions which would be difficult to achieve using two-electron chemistry.  The enzymes use a variety of metals, either as endogenous ligands or as bound cofactors, to generate radicals.  Identification of these radical species is necessary to obtain a complete understanding of […]

Lighting the future with boron carbides: A new approach to green chemistry – Dr. Jesse J. Sabatini

Abstract:  As the “center of mass” for all Department of Defense-related research, the US Army’s Armament Research, Development and Engineering Command (ARDEC) at Picatinny Arsenal has been the leader in carrying out an abundance of projects in the field of energetic materials.  Over the past decade, increasing environmental regulations have called into question many of […]

Recent innovations in alkyne chemistry – Professor Gregory Dudley

Professor Dudley’s website Research in the Dudley Lab is designed to further the science and practice of organic chemistry. Several new methods are under development, including a tandem nucleophilic addition / C–C bond-cleaving fragmentation reaction that generates alkynes. The research seminar will focus on this on-going “alkynogenic fragmentation” methodology. Related applications to the synthesis of […]

UVA Green Chemistry Seminar – Endocrine disruption: Why we need to design molecules that avoid it, and how that might happen – Dr. Pete Myers

*Please note this seminar will be held on Wednesday, October 19th at 6:30 pm in Campbell Hall 160.* Dr. Myers’ website Abstract: By allowing chemicals like bisphenol A to enter into widespread use in consumer products, we have created widespread exposures.  This happened for several reasons, including inadequacies and false assumptions in the methods used […]

Functional 1,2,3-Triazoles: chemistry beyond “click” – Professor Michael Shi

Professor Shi’s website Abstract: The functional 1,2,3-triazole derivatives were developed as ligands in metal coordination. New reactivity was discovered associated with this new class of compounds. Interesting reactivity including the improved thermal and substrate stability in gold catalysis, new photoactive ligands in promoting light mediated catalysis, stable boron complexes and alternated radical reactivity in iron […]

Graduate Studies Handbook

Structure, function, and antibiotic resistance of the outer membrane of Pseudomonas aeruginosa – Professor Lukas Tamm

Professor Tamm’s website Abstract:  Pseudomonas aeruginosa is a major nosocomial pathogen that infects cystic fibrosis and immunocompromised patients.  The impermeability of the P. aeruginosa outer membrane contributes substantially to the notorious antibiotic resistance of this human pathogen. This impermeability is partially imparted by the outer membrane protein H (OprH). I will describe the structure of […]

Structure determination of membrane proteins by solid-state NMR: Uniaxial alignment, spectroscopic assignment, and structure calculations – Professor Alex Nevzorov

Professor Nevzorov’s website Abstract:  “Oriented-sample NMR (OS NMR) has emerged as a powerful technique for structure determination of membrane proteins in their native lipid environment.   In OS NMR, the structural information is directly contained in the angular-dependent NMR frequencies. Several issues of critical importance for OS NMR are addressed.  The first one is line narrowing […]

Energy management in organic solar cells – Professor Mark Thompson

Professor Thompson’s website Abstract:  We have taken a materials intensive approach to developing an understanding of the mechanism of photocurrent and photovoltage generation in organic photovoltaic devices (OPVs).   We have explored the use of metal porphyrin complexes as donor materials in OPVs.  The complexes we have chosen have high nonplanar structures in the ground state […]

IRELAND LECTURE: Evolution of function in the isoprenoid biosynthetic pathway through control of regiochemistry – Professor Dale Poulter

Professor Poulter’s website Abstract:  Virtually all of the organic molecules required to support life are the products of biosynthesis.  The enzymes that catalyze the individual reactions in biosynthetic pathways are typically highly evolved to efficiently synthesize a single stereochemically defined product.  Recent advances in genomics and X- ray crystallography have revealed similarities among biosynthetic enzymes […]

Applications of new properties resulting from the confinement effects on the nanoscale in environmental research, in solar energy conversion and in cancer nano-medicine – Professor Mostafa El-Sayed

Professor El-Sayed’s website Abstract:  The presentation will discuss three topics each making use of the interesting properties resulting from the confinement effects on the nanoscale with applications to environmental research, to solar energy conversion and to nanomedicine. In the first part of the presentation, we show that catalysis with hollow nanoparticles is more efficient when […]

Copper-catalyzed borylation and inhibition of protein-RNA interactions – Professor Webster Santos

Professor Santos’ website Abstract:  This seminar will describe our efforts in developing novel diboron reagents and their application in the catalytic copper-catalyzed β-borylation of electron-deficient olefins such as α,β-unsaturated ketones, esters, aldehydes, and allenoates. Mechanistic aspects as well as environmentally friendly versions will be discussed.  In a separate project, we will discuss a strategy for […]

Creation and reaction of solvated electrons at the vacuum-liquid interface – Professor Gil Nathanson

Professor Nathanson’s website Abstract:  Over the last 70 years, thousands of reactions between solvated electrons and dissolved species have been investigated in water and other protic solvents.  Electrons born at the surface of the solvent, however, may react differently than those created within it.  In this talk, I will describe gas-liquid scattering experiments using sodium […]