Events & Seminars > Upcoming Seminars

From C-C agostic interactions to C-H bond activation

Despite their relative scarcity, agostic complexes where a CC,[1] rather than a CH, bond interacts with a main group or transition metal have been attracting strong attention recently. This stems from their involvement in metallacyclobutanes that are intermediates in alkene metathesis reactions,[2] and also in their ability to model CC s-complexes and CC bond cleavage.[3] […]

Discovery of a New Type of Catalytic Site Involving Nano-Gold Particles

     Just two years ago, Izzie Green, working in my group in Chemistry at UVa, along with Matt Neurock and Wenjie Tang in Chemical Engineering, discovered a new type of catalytic site involving ~ 3nm diameter Au particles supported on TiO2[1,2].  This site has the remarkable property of catalyzing the oxidation of a variety of […]

Chemistry for Global Health: designing new interventions against Anopheles gambiae, the malaria mosquito

Global Health is the health of populations in a global context, that transcends the perspectives and concerns of individual nations. What impact can organic chemistry have on Global Health? In this seminar I will describe our multidisciplinary, collaborative research to develop new human-safe insecticides against Anopheles gambiae, the “most dangerous animal,” responsible for nearly 700,000 deaths annually. […]

Does Evolution Care About Quantum Mechanics? Electrons, Bioenergetics, and Life

Charge-transfer reactions lie at the heart of photosynthesis and respiration, biocatalysis, disease-related oxidative stress, and nanoscience.  Many charge-transfer reactions involve electron tunneling, and are therefore intrinsically quantum mechanical in nature. Evolution is challenged to manipulate the propagation of electrons in these complex and fluctuating systems [1,2].  The aim of my presentation is to summarize the […]

Molecular Dynamics, Spin Relaxatin, and Magnetic Image Contrast

Beyond The Periodic Table: Role of Superatoms

Nearly twenty years ago it was predicted that stable atomic clusters with specific size and composition and mimicking the chemistry of atoms in the periodic table can be designed and synthesized [1]. These clusters known as “superatoms” can then form the building blocks of a new three-dimensional periodic table and the basis for cluster assembled […]

Hydrogel-Actuated Integrated Responsive Systems (HAIRS): Moving Towards Adaptive, Homeostatic Materials

Dynamic structures that respond reversibly to changes in their environment are central to self-regulating thermal and lighting systems, targeted drug delivery, sensors, and self-propelled locomotion. Since an adaptive change requires energy input, an ideal strategy would be to design materials that harvest energy directly from the environment and use it to drive an appropriate response. […]

Pathways to Chemical Complexity During Star- and Planet-Formation – Dr. Karin Öberg

Dr. Öberg’s Website Please note that this is a Chemistry Faculty Hire seminar. Abstract: Complex organic molecules (>6 atoms) have been detected toward low- and high-mass protostars, galactic center clouds, protostellar outflows and comets, demonstrating the existence of efficient astrophysical pathways to chemical complexity. The detected molecules all reside in the gas. Yet they probably […]

Rescheduled for April 26, 2013 – How Bugs Escape Drugs – Professor Richard Brennan

HECHT LECTURE: On de novo Purine Biosynthesis: The Purinosome – Professor Steve Benkovic

Professor Benkovic’s website Abstract: For several decades sequential metabolic enzymes had long been hypothesized to form multi-enzyme complexes in cells to regulate metabolic flux.  Single molecule fluorescence imaging in live cells of the enzymes involved in human de novo purine biosynthesis uncovered the reversible formation of a metabolic multi-enzyme complex, the “purinosome”.  Purinosome formation was […]

Reactions of Late Transition Metal Alkyl and Hydride Complexes with Molecular Oxygen – Professor Karen Goldberg

Professor Goldberg’s website Abstract:  From environmental and economic standpoints, molecular oxygen represents an ideal oxidant for chemical transformations.  It is readily available, inexpensive (particularly if used without separation from air) and environmentally benign. While oxygen is currently used as an oxidant for many large-scale chemical oxidations, there are numerous other transformations for which researchers have […]

JEFFERSON LECTURE: Monitoring and Modeling Techniques to Evaluate Chemistry in Streams with Focus on Continuous Water Quality that Provide Insights into Urban Stream Processes on Short Temporal Scales – Dr. Cherie V. Miller

Dr. Miller’s website

From Hydrocarbon Combustion Radicals to Gas-Liquid Interfacial Collision Dynamics: Insights from Quantum State-Resolved Studies – Professor David Nesbitt

Professor Nesbitt’s website Abstract:  One of the traditions of physical chemistry is trying to break down complicated problems into simpler ones that may be more readily tested at the fundamental level by comparison between experiment and theory. This talk will address two areas of recent research interest in our group focusing on quite different but […]

Plasmon-Controlled Fluorescence: Applications to Biochemistry and Biotechnology – Professor Joe Lakowicz

Professor Lakowicz’ website Abstract:  Fluorescence spectroscopy is widely used in chemical and biological research. Until recently essentially all fluorescence experiments were performed in the far-field regime. By far-field we mean at least several wavelengths from the fluorophore. In recent years there has been a growing interest in the interactions of fluorophores with metallic surfaces or […]

Multianalyte Microphysiometry: Microfluidic Electrochemistry for Metabolic Profiling – Professor David Cliffel

Professor Cliffel’s website Abstract: Microphysiometry is a technique that measures the pH changes produced by the energy metabolism of approximately 100,000 live cells in a 3 microliter chamber.  Our group has added multiple additional electrochemical sensors for metabolic analytes into this chamber to give a complete dynamical picture of the live cell population.  Our four-analyte […]

A Singular View of the Genome – Professor David Schwartz

Professor Schwartz’ website Abstract: Technological advances broaden our understanding of genomes, and new approaches employing single molecule analytes offer unique advantages for the discovery and characterization of genomic alterations complementing discernment of single nucleotide polymorphisms (SNPs) and copy number variants (CNVs). CNVs commonly represent genomic events, such as amplifications and deletions usually found by DNA […]

Dynamic and Morphological Characterization of Polymeric Membrane Materials on the Molecular Level by Solid-State NMR – Professor Sungsool Wi

Professor Wi’s website My research focuses on the utilization of solid-state NMR spectroscopy for studying the structure and dynamics of modern polymeric materials, such as fuel cell membranes and reverse osmosis (RO) membranes. Presented in this talk are the dynamic and morphological features found on di-sulfonated poly(arylene ether sulfone) random block copolymers that are developed […]

Bioinorganic Chemistry of Titanium in Medicine and the Environment – Professor Ann Valentine

Professor Valentine’s webpage

Characterization of biomacromolecular solutions and nanostructured materials by small-angle X-ray scattering (SAXS) – Dr. Dmitri Svergun

This event is co-sponsored by Molecular Physiology and Biological Physics and The Department of Chemistry. Refreshments at 3:45 pm

Cluster Formation by Ras Membrane Anchors – Dr. Alemayehu Gorfe

Co-sponsored by the Departments of Chemistry & Molecular Physiology and Biological Physics Dr. Alemayehu Gorfe’s website

EPR Spectroscopy on Planar Surfaces: From Single Crystals to Adsorbed Proteins – Professor Thomas Risse

Professor Risse’s Website

Metal-Ligand Multiple Bonds: From Alkane Activation and Dehydrogenation to Some Catalytic Prospects – Professor Dan Mindiola

Professor Mindiola’s Website Abstract: Methane is the most abundant but least reactive of the family of alkanes, and current vast supplies constitute nearly 70-90% of the natural gas reserves in the world, a value which now heavily competes with imminent dwindling of petroleum feedstock. Both natural gas and petroleum account for more than half the […]

Catalytic C-H Functionalization: Interplay Between Catalyst Design and Mechanism – Professor Melanie Sanford

Professor Sanford’s Website   Abstract: This seminar will discuss my group’s development of new transition metal catalyzed reactions for the selective functionalization of carbon–hydrogen bonds. These reactions provide potentially ‘greener’ routes for the development of new pharmaceuticals and other biologically active molecules. They also offer opportunities for utilizing natural gas as a transportation fuel. The […]

Cathepsin K Inhibitors for the Treatment of Osteoporosis: An Example of the Drug Discovery Process – Dr. David Deaton

Hot Electrons and a Path Towards the Ultimate Solar Cell – Professor Xiaoyang Zhu

Professor Zhu’s Website   Abstract: This lecture will address a fundamental question related to the use of nanomaterials in solar energy — namely, whether semiconductor nanocrystals can help surpass the efficiency limits in conventional solar cells. As is known as the so-called “Shockley-Queisser” limit, the maximum theoretical efficiency of a single-junction solar cell, such as […]

IRELAND LECTURE: New Methodology for Asymmetric Synthesis with Application to the Construction of Stereochemically Complex Molecules – Professor Robert Boeckman, Jr.

Professor Boeckman’s Website Abstract: New asymmetric synthesis methodology employing isoamidium ions as Diels-Alder dienophiles will be discussed.  These dienophiles provide regio- and stereospecific access to enatiomerically pure g-butyrolactones.  Extensions of retroClaisen methodology to the synthesis of enantiometically pure 8-membered nitrogen heterocycles will also be presented.  These two methodologies were conceived as part of a strategy […]

NMR Relaxation Experiments for Proteins at High-Magnetic Field Strength – Professor Rieko Ishima

Professor Ishima’s Website

Developing Rapid Tools for In Vivo Measurements: Insights into Dopamine, Serotonin, and Adenosine Signaling – Professor Jill Venton

Professor Venton’s Website

Multifunctional Polymeric Catalysts and Reagents – Professor Patrick Toy

The Best Is Yet To Be: New Chemical Models of Stellar and Planetary Formation – Professor Eric Herbst

Professor Herbst’s website Abstract:  Astrochemistry is the study of molecules throughout the universe, including how they are formed and what they tell us about the physical conditions where they reside. The subject is most closely connected to the study of so‐called interstellar clouds, which are large objects consisting of gas and tiny dust particles. The […]