Bioanalytical research efforts involve the design, development, and application of state-of-the-art instrumentation for interrogating biological systems in ways that cannot be addressed using conventional analytical methods. The core bioanalytical faculty consist of Profs. Demas, Hunt, Landers, and Venton, whose expertise cover sensors, mass spectrometry, microfluidics and analytical neurochemistry. In addition, a number of other groups have bioanalytical interests including those of Bryant, Fraser, Geysen, Harrison, Lehman, Pu and Yates labs. These groups bring major instrument-based areas of interest that include electron spin resonance, nuclear magnetic resonance, surface science, modeling and spectroscopy. This allows for a tremendous bandwidth of analytical methodologies to be brought to bear on arange of fundamental and applied problems, such as proteomics, genomics, medical diagnostics, forensics, neurochemical analysis, molecular probes, and understanding protein structure. Considerable effort is directed toward the development of new instrumentation and measurement techniques that advance the present state of the art.