Sarah Elkin

Sarah Elkin

Specialization in Biochemistry
Research with Prof. Linda Columbus

Sarah Elkin is from Houston, Texas and graduated from M. B. Lamar High School in 2008. Sarah has been working in the Columbus lab since the spring of her second year on characterizing the function of the protein Ta0880 from the thermophilic bacterium Thermoplasma acidophilum. Based on the protein’s structure, it was putatively identified as a ribokinase. However, her research has shown that there is no evidence to support ribokinase activity. Instead, the protein Ta0880 appears to use nucleosides as substrates rather than ribose. She is currently investigating additional substrates and optimizing solution conditions to quantify the kinetic parameters of Ta0880 activity.