Lee, John

John Lee

John was born in Madison, Wisconsin and graduated from Governor Thomas Johnson High School in Frederick, MD. He is pursuing a Bachelors of Science in Chemistry with a specialization in biochemistry with the addition of ACS certification.

His research is in Dr. Laubach’s lab in the Division of Thoracic & Cardiovascular Surgery Lab. The lab focuses on attenuating Lung ischemia-reperfusion (IR) injury that occurs when oxygen carried in the blood returns to tissue after periods of halted blood flow and oxygen deprivation. The project is focusing on the use of mesenchymal stem cells (MSCs) to attenuate IR injury. Human MSCs have been shown to modulate allogenic immune responses to alter cytokine secretions of dendritic cells, T cells, and Natural Killer T cells to induce anti-inflammatory phenotypes. The thesis project is focusing on simulating IR injury in vitro by exposing cells to hypoxia-reoxygenation, analyzing possible methods of cytokine inhibition, and utilizing them for therapeutic purposes.